BDBM351589 N-(4-bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(quinolin-5-yl)acetamide::US9796706, Compound 33

SMILES Brc1csc(NC(=O)Cc2cccc3ncccc23)c1-c1ncn[nH]1

InChI Key InChIKey=IHBXLESUKAAQDQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351589   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351589(N-(4-bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)...)
Affinity DataIC50: <100nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent